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KMID : 1161220240670030140
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Clinical and Experimental Pediatrics
2024 Volume.67 No. 3 p.140 ~ p.148
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Practical issues of oral immunotherapy for egg or milk allergy
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Kim Su-Kyung
Ahn Kang-Mo
Kim Ji-Hyun
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Abstract
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Oral immunotherapy (OIT) has been recommended to reduce parental burden related to strict allergen avoidance and induce desensitization and immune tolerance for patients with long-lasting allergies to hen’s eggs (HE) or cow’s milk (CM). OIT should be monitored by pediatric allergists specializing in OIT and oral food challenge tests to manage allergic reactions. Although a previous history of anaphylaxis or multiple food allergies is not a contraindication to OIT, it is contraindicated if the patienthas uncontrolled asthma, a malignancy, active systemic autoimmune disorders, or diseases requiring treatment with beta-blockers. A variety of OIT protocols have been developed to ensure better outcomes and safe up-dosing, including adjunctive therapies with biologics.
This review provides insight into the practical issues of various immunotherapy options for children with HEorCM
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KEYWORD
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Egg allergy, Food allergy, Milk allergy, Oral food challenge, Oral immunotherapy
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